Keywords

• Saxagliptin
• 361442-04-8
• C18H25N3O2

Quick Details

• ProName: Saxagliptin
• CasNo: 361442-04-8
• Molecular Formula: C18h25n3o2
• Appearance: Powder
• Application: Pharmaceutical industry
• DeliveryTime: Stock
• PackAge: 1kg Per Foil Bag, 10 Bags Per Carton. ...
• Port: Shanghai/tianjin
• ProductionCapacity: /
• Purity: 99%
• Storage: Cool Dry Place
• Transportation: By sea
• LimitNum: 100 Gram

Superiority

Our own factory produces direct sales with absolute price advantage

Details

Saxagliptin is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs.This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.

Function of Saxagliptin

AlPost-administration of saxagliptin, GLP-1 and GIP levels rise up to 2- to 3- fold. Because it is very selective of DPP-4 inhibition, there are fewer systemic side effects. Saxagliptin inhibits DPP-4 enzyme activity for a 24-hour period. It also decreased glucagon concentrations s. The half  inhibitory concentration (IC50) is 0.5 nmol/L. Saxagliptin did not prolong the QTc interval to a clinically significant degree.

Application of Saxagliptin
 

Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor antidiabetic for the treatment of type 2 diabetes. DPP-4 inhibitors are a class of compounds that work by affecting the action of natural hormones in the body called incretins. Incretins decrease blood sugar by increasing consumption of sugar by the body,, and by reducing production of sugar by the liver. [Bristol-Myers Squibb Press Release] DPP-4 is a membrane associated peptidase which is found in many tissues, lymphocytes and plasma. DPP-4 has two main