Business Type:Trading Company
Product Certification&
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Country: China (Mainland)
Business Type:Trading Company
Tel: 15350525905
Tel: 13315186550
Tel: 17798195659
Tel: 19061935658
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Tel: 15350525905
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Province/state: Hebei
City: Shijiazhuang
Street: 518, Mansion No. 3, Guang 'an Street, Chang 'an District, Shijiazhuang, Hebei
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Tyrothricin is a mixture of polypeptides, consisting of 50%-70% tyrocidines and 25%-50% gramicidins. The group of tyrocidines is basic, cyclic peptides, whereas the fraction of gramicidins is neutral, linear peptides. Besides physiological and essential L-amino acids, the components of Tyrothricin also contain D-amino acids. Tyrothricin is produced by the gram-positive aerobic sporeforming bacterium Bacillus brevis (Strain ATCC 8185) during its sporulation phase via the nonribosomal pathway. The efficacy spectrum of Tyrothricin mainly covers gram-positive but also several gram-negative bacteria. Corynebacteria and staphylococci show a broader range of Tyrothricin concentrations for inhibition (2-256 μg/mL). In contrast to the gramicidin fraction alone, Tyrothricin is able to inhibit all Staphylococcus strains at a maximum concentration of 128 μg/mL. Among the gram-negative organisms, gonococci and meningococci were the most sensitive germs (96 μg/mL). Tyrothricin exerts fungicidal effects on a variety of Candida species. Tyrothricin shows an anti-infectious activity against parainfluenza virus (type Sendai). |