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CAS NO.81524-75-6
6-Azido-1H-indole is an organic compound. It is a colorless crystal that is easily soluble in organic solvents such as ethanol, dimethylformamide, and toluene, and slightly soluble in water.
This compound has multiple applications. One important use is as an intermediate in organic synthesis. It can be used for the synthesis of indole compounds, fluorescent dyes, and bioactive substances. 6-Azido-1H-indole can also be used to prepare organic explosives and high-energy compounds.
There are various methods for preparing 6-azido-1H-indole. A common method is to react benzyl alcohol with triethylamine to obtain benzyl ester, followed by ester hydrolysis to obtain 1H indole. Next, nitrogen is introduced into the ketone solution to form an azide group.
6-Azido-1H-indole is a potentially hazardous chemical. It is explosive and should be avoided from contact with flammable materials, oxidants, strong acids, and other substances. Appropriate protective equipment such as chemical goggles and gloves should be worn during handling. When storing, it should be kept away from sources of fire and high temperature environments to ensure safe use. Proper laboratory operating procedures and safety measures must be followed when using or handling 6-azido-1H-indole.